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New
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GUSD Minting
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Vir Biotechnology Reports Positive Updated Phase 1 Results for PSMA-targeting, PRO-XTEN® Dual-masked T-Cell Engager VIR-5500 in Patients with Metastatic Prostate Cancer
Vir Biotechnology announced positive updated Phase 1 results for VIR-5500, a PSMA-targeting, PRO-XTEN® dual-masked T-cell engager, in patients with metastatic castration-resistant prostate cancer. The study showed a favorable safety profile with no dose-limiting toxicities and significant anti-tumor activity, including PSA50 and PSA90 declines, and objective responses in highly pre-treated patients. The company plans to advance to dose-expansion cohorts and initiate a registrational trial in 2027, highlighting VIR-5500’s potential for improving outcomes in prostate cancer.